Rhinovirus Wheezing Illness and Genetic Risk of Childhood-Onset Asthma
نویسندگان
چکیده
منابع مشابه
Rhinovirus wheezing illness and genetic risk of childhood-onset asthma.
BACKGROUND Both genetic variation at the 17q21 locus and virus-induced respiratory wheezing illnesses are associated with the development of asthma. Our aim was to determine the effects of these two factors on the risk of asthma in the Childhood Origins of Asthma (COAST) and the Copenhagen Prospective Study on Asthma in Childhood (COPSAC) birth cohorts. METHODS We tested genotypes at the 17q2...
متن کاملAssociation between rhinovirus wheezing illness and the development of childhood asthma: a meta-analysis
OBJECTIVE The relation between early-life rhinovirus (RV) wheezing illness and later onset of wheezing/asthma remains a subject of debate. Therefore, we conducted this meta-analysis to evaluate the association between RV wheezing illness in the first 3 years of life and the subsequent development of wheezing/asthma. DESIGN Systematic review and meta-analysis. METHODS The PubMed, EMBASE, Web...
متن کاملAmbient Environmental risk factors for childhood wheezing illness.
It is a great consensus in the scientific community that environmental factors, such as weather conditions and ambient air pollution, have vital impacts on respiratory diseases. Further, these factors imply the potential to have many significant impacts on aeroallergens, and therefore related diseases such as asthma and allergic rhinitis. The impacts are more pronounced in sensitive groups of p...
متن کاملRhinovirus and childhood asthma: an update
Asthma is recognized as a complex disease resulting from interactions between multiple genetic and environmental factors. Accumulating evidence suggests that respiratory viral infections in early life constitute a major environmental risk factor for the development of childhood asthma. Respiratory viral infections have also been recognized as the most common cause of asthma exacerbation. The ad...
متن کاملRhinovirus illnesses during infancy predict subsequent childhood wheezing.
BACKGROUND The contribution of viral respiratory infections during infancy to the development of subsequent wheezing and/or allergic diseases in early childhood is not established. OBJECTIVE To evaluate these relationships prospectively from birth to 3 years of age in 285 children genetically at high risk for developing allergic respiratory diseases. METHODS By using nasal lavage, the relat...
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ژورنال
عنوان ژورنال: PEDIATRICS
سال: 2013
ISSN: 0031-4005,1098-4275
DOI: 10.1542/peds.2013-2294ddd